MODULATION OF THE CONTRACTILE ACTIVITY IN THE SMOOTH MUSCLES OF THE COLON BY BIOLOGICALLY ACTIVE SUBSTANCES
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Abstract
Biologically active substances (NH4Cl, calcium channel blocker foridon, potassium channel activator flokalin, compound "C") modulated of the frequency and amplitude of phase components and spontaneous motor activity in smooth muscles with different frequency and intensity. It was established that the level of extracellular and intracellular pH, functioning of calcium and potassium channels of plasmatic membrane play an important role in the dynamics of motor activity of smooth sigmoid myocytes
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