Analysis of the central blood flow characteristics among the participants of the research, who have chronic effects of negative environmental factors in the workplace

V. V. Pshybelskyj, O. A. Zhuravlov, T. Ya. Shevchuk, O. V. Zhuravlova


Introduction. The problem of the public health of Ukraine in our country is acute and requires a moderate rise. There are steady tendencies in the increased incidence and the disease dissemination in Ukraine. Currently, the particular scientific researches proved that the bad state of the environment, air, ground and water pollution and the influence of the other negative factors of environment on the human body can be the reasons of the increased incidence, cardiovascular disease in particular.

Purpose. The main purpose of the research was to study the dependence of the parameters of the central blood flow and the type of body structure of the workers of the agro-industrial sector and industrial enterprises that undergo chronic effects of a complex of harmful environmental factors.

Methods. In the lens of the experiment, 90 people were participants, male aged from 21 to 35 years old. For the purpose of the study all the participants were divided into 3 groups: 1) the population live at least in an ecologically pure zone; 2) the residents of the agrarian districts of the Volyn Region, which are seized in the agricultural area and positively correlated with fertilizers and pesticides; 3) people who work at the enterprises in Lutsk. Proportionality of development and structure of the body of the subjects were studied by calculating the Pignet (IP) index. The study of the central hemodynamic was carried out with the help of the “Askold” (“Kyiv”, 1998), with the use of the method of tetrapolarity reographism by Kubicek. The reograms recording was carried out at the time of the spontaneous respiration and the duration of the inhomogeneous exhalation.

Results. Correlation analysis of the indicators of central blood flow and anthropometric indicators showed that in the control group there is a high level of direct dependence of practically all of the studied parameters of the central blood flow from the Pignet index. Thus, in particular, the value of the minute volume of blood flow (r = 0.49), volume of ejection rate (r = 0.31), myocardial capacity (r = 0.34), shock index (r = 0.32) and cardiac index (r = 0.47) is directly proportional to the given index, and the index of the total peripheral resistance (r = -0.41) reveals an inverse relationship.

The grounding of the division of the subjects studied into groups, taking into account the index of their constitution (Pignet index), was manifested in the fact that most of the studied parameters were characterized by a significant number of statistically significant correlation relations with this indicator. Such a feature of the obtained results made it possible to analyze the parameters of the cardio-respiratory system of people who have been exposed to harmful factors in the workplace for a long time, taking into account the groups allocated on graduations, which are based on the value of the Pignet index.

Analysis of the central blood flow characteristics among the participants of the research, who have chronic effects of negative environmental factors in the workplace (both agro-industrial and industrial) revealed significant differences between the given groups and the group of people from relatively environmentally pure zones in terms of the impact volume of the bloodstream and the capacity of the myocardium . However, the lack of significant differences in the values of the minute volume of blood and energy consumption by the myocardium may indicate a certain compensatory change due to the strengthening of regulatory mechanisms that provide the necessary level of blood supply to the tissues of the body and the absence of organic lesions as the structures of the cardiovascular system, and regulatory circuits of the nervous and endocrine systems that provide a regulation link.

Conclusion. People who exposed to negative environmental factors in the workplace, absolute anthropometric indices (age, height, weight, chest) and integral indices (Pignet index) did not differ from those in the control group. The largest number of statistically significant correlation relationships was found in the control group of the participants between functional parameters of the cardiovascular system and the Pignet index, while among people, who have adverse working conditions, such relationships are practically absent. People undergo chronic effects of negative environmental factors in the workplace (both agro-industrial and industrial), there were significant differences in comparison with the group of people from relatively environmentally pure regions in terms of the impact volume of blood flow and the capacity of the myocardium, but these changes have compensatory character. Taking into account the type of body structure of the participants showed that the greatest number of differences between the experimental groups and control was found among mesomorphic people: significant differences are noted in the indicators of myocardial capacity and specific peripheral resistance.


central hemodynamics; ecological factors; factors of manufacturing; type of body structure


Agarkov, V. I. Bugasheva, N. V., Koktyshev, I. V. et al. (2007). Regularities and features of morphofunctional health indicators of adolescents permanently living in social and ecological conditions of Donbass. Vestnik gigieny i epidemiologii (Bulletin of Hygiene and Epidemiology), 1, 3-7. (in Rus.)

Zhuravlov, O. A. (2005) Features of the amplitude-time characteristics of cerebral hemodynamics during performing cognitive tasks in students who lived for a long time in conditions of radiation pollution. L’viv, 216-217. (in Ukr.)

Mihalev, V. P., Adamovich, B. L. (1997) Hygienic assessment of radioactive contamination of the environment. Gigiena i sanitarija (Hygiene and Sanitation), 3, 36-41. (in Rus.)

Kaverin, A. V. Shankin, A. A., Shankina, G. I. (2015) Impact of environmental factors on physical development and population health. Vestnik Mordovskogo universiteta (Bulletin of the Mordovian University), 2, 87-97. (in Rus.)

Judin, G. V. (2003) Formation of somatotypes in children and adolescents of school age under the influence of anthropo-technogenic chemical factors. Morfologija (Morphology), 123, 3, 86-88. (in Rus.)

Hoppin, J. A., Umbach, D. M., London, S. J. et al. (2003). Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smoking. Occup. Environ. Med., 60, 3.

Grishchenko, S. V. Grishchenko, I. I., Abakumova, A. V. et al. (2007) Hygienic assessment of the environmental condition of the Donetsk region and its degree of danger to public health. Vestnik gigieny i epidemiologii (Bulletin of Hygiene and Epidemiology, 11, 1, 8-12. (in Rus.)

Maroni, M., Fanetti, A. C., Metruccio, F. (2006). Risk assessment and management of occupational exposure to pesticides in agriculture. Med. Lav., 97,430-437.

Antoniuk, O. P. (2012) Prediction of dependency between the morbidity level in Kryvyi Rig city and the influence of technogenic pollution. Ekonomicnij Casopis-XXI (Economic Annals-XXI), 1/2, 59-67. (in Ukr.)

Ermolenko, G. V. (2007) Features of the functioning of the leading adaptation systems and the psychophysiological status of adolescents living in conditions of chemical pollution. Moscow. (in Rus.)

Beseler, C. L. Stallones, L. (2009) Pesticide poisoning and respiratory disorders in Colorado farm residents. J. Agric. Saf. Health, 15, 327-334.

Payán-Rentería, R., Garibay-Chávez, G., Rangel-Ascencio, R. et al. (2012) Effect of chronic pesticide exposure in farm workers of a Mexico community. Arch. Environ. Occup. Health. 67, 22-30.

Libanova, E.M. (2006) The forecast of population mortality trends in Ukraine. Demografija ta social'na ekonomika (Demography and Social Economy), 1, 23-37. (in Ukr.)

Gruzeva, T. S. (2010) The influence of ecological factors on the global disease formation. Naukovyi visnyk Natsionalnoho medychnoho universytetu im. O. O. Bohomoltsia (Scientific Bulletin of the National Medical University named after O. O. Bohomolets), 27, 167-168. (in Ukr.)

Bunak, V.V. (1931). Anthropometric research methodology. Moscow-Leningrad. (in Rus.)

Kotysheva, E. N. Dzyundzy, N. A., Bolotskaya, M. Yu. (2008). Analysis of anthropometric indicators of the physical development of children aged 5-7 years in an industrial city. Pediatrija (Pediatrics), 2, 140-143.(in Rus.)

Ronkin, M. A., Ivanov, L. B. (1997). Rheography in clinical practice. Moscow. (in Rus.)

Clasey, J. L., Kanaley, J. A., Widemanetal, L.Validity of methods of body composition assessment in young and older men and women. J. Appl. Physiol., 86, № 5, 1728-1738.

Bezpalova, N. M. (2010). Morpho-functional patterns of physical development of students, depending on the prevailing type of autonomous nervous system. Ternopil. (in Ukr.)

Bahtoyarov, P. D. (2003). Initial violations of a blood supply of a brain for working major industrial firm of Donets Basin, their correction by methods magnetotherapy and reflexotherapy. Kyiv. (in Ukr.)

Chistilina, E.S., Gaiduk, S.G. (2000). Peculiarities of changes in heart and vascular conditions in functional studies among participants in the liquidation of the Chernobyl accident in the remote period. Mezhdunarodnyj zhurnal radiacionnoj mediciny (Intern. Journal of Radiations. Medicine), 1-2, 313-315. (in Rus.)

Barnett, H. L., Keel, P. K., Conoscenti, L. M. (2001). Body type preferences in Asian and Caucasian college studentas. Sex Roles, 45, 11-12, 867-878.

Коtsаn, І., Zhuravlov, O., Kozachuk, N. (2006). Psychophysiological features of students, which live in zone of the radiological control. Visnyk Prykarpatskoho universytetu. Seriia Biolohiia (Bulletin of the Precarpathian University. Series Biology), 6, 190-196. (in Ukr.)

Chumakova, O.L., Glebov, V.V. (2013). The impact of anthropogenic factors of a metropolis on the adaptation of children and adolescents. Uspehi sovremennogo estestvoznanija (Successes of modern natural science), 8, 60-61. (in Rus.)

Full Text: PDF


  • There are currently no refbacks.
2014 2 36
2015 2 19
2016 1 2
2017 1 2
2018 1 2
2019 1  



Journal Content