Analysis of the central blood flow characteristics among the participants of the research, who have chronic effects of negative environmental factors in the workplace
Introduction. The problem of the public health of Ukraine in our country is acute and requires a moderate rise. There are steady tendencies in the increased incidence and the disease dissemination in Ukraine. Currently, the particular scientific researches proved that the bad state of the environment, air, ground and water pollution and the influence of the other negative factors of environment on the human body can be the reasons of the increased incidence, cardiovascular disease in particular.
Purpose. The main purpose of the research was to study the dependence of the parameters of the central blood flow and the type of body structure of the workers of the agro-industrial sector and industrial enterprises that undergo chronic effects of a complex of harmful environmental factors.
Methods. In the lens of the experiment, 90 people were participants, male aged from 21 to 35 years old. For the purpose of the study all the participants were divided into 3 groups: 1) the population live at least in an ecologically pure zone; 2) the residents of the agrarian districts of the Volyn Region, which are seized in the agricultural area and positively correlated with fertilizers and pesticides; 3) people who work at the enterprises in Lutsk. Proportionality of development and structure of the body of the subjects were studied by calculating the Pignet (IP) index. The study of the central hemodynamic was carried out with the help of the “Askold” (“Kyiv”, 1998), with the use of the method of tetrapolarity reographism by Kubicek. The reograms recording was carried out at the time of the spontaneous respiration and the duration of the inhomogeneous exhalation.
Results. Correlation analysis of the indicators of central blood flow and anthropometric indicators showed that in the control group there is a high level of direct dependence of practically all of the studied parameters of the central blood flow from the Pignet index. Thus, in particular, the value of the minute volume of blood flow (r = 0.49), volume of ejection rate (r = 0.31), myocardial capacity (r = 0.34), shock index (r = 0.32) and cardiac index (r = 0.47) is directly proportional to the given index, and the index of the total peripheral resistance (r = -0.41) reveals an inverse relationship.
The grounding of the division of the subjects studied into groups, taking into account the index of their constitution (Pignet index), was manifested in the fact that most of the studied parameters were characterized by a significant number of statistically significant correlation relations with this indicator. Such a feature of the obtained results made it possible to analyze the parameters of the cardio-respiratory system of people who have been exposed to harmful factors in the workplace for a long time, taking into account the groups allocated on graduations, which are based on the value of the Pignet index.
Analysis of the central blood flow characteristics among the participants of the research, who have chronic effects of negative environmental factors in the workplace (both agro-industrial and industrial) revealed significant differences between the given groups and the group of people from relatively environmentally pure zones in terms of the impact volume of the bloodstream and the capacity of the myocardium . However, the lack of significant differences in the values of the minute volume of blood and energy consumption by the myocardium may indicate a certain compensatory change due to the strengthening of regulatory mechanisms that provide the necessary level of blood supply to the tissues of the body and the absence of organic lesions as the structures of the cardiovascular system, and regulatory circuits of the nervous and endocrine systems that provide a regulation link.
Conclusion. People who exposed to negative environmental factors in the workplace, absolute anthropometric indices (age, height, weight, chest) and integral indices (Pignet index) did not differ from those in the control group. The largest number of statistically significant correlation relationships was found in the control group of the participants between functional parameters of the cardiovascular system and the Pignet index, while among people, who have adverse working conditions, such relationships are practically absent. People undergo chronic effects of negative environmental factors in the workplace (both agro-industrial and industrial), there were significant differences in comparison with the group of people from relatively environmentally pure regions in terms of the impact volume of blood flow and the capacity of the myocardium, but these changes have compensatory character. Taking into account the type of body structure of the participants showed that the greatest number of differences between the experimental groups and control was found among mesomorphic people: significant differences are noted in the indicators of myocardial capacity and specific peripheral resistance.
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