Features of brain bioelectrical activity in Parkinson's disease

N. S. Kozhemyako, S. A. Kryzhanovskyi, A. O. Cherninskyi, I. G. Zyma, I. N. Karaban

Abstract


There is a high range of investigations that show changes of networks structure in the rest state as a result of progress of many difference diseases. But there are no experimental data that gives us a generally accept point of view about effects of Parkinson’s disease. In our opinion such changes may affect basic functional brain state characteristics, such as EEG-activity of brain. We made a comparison of spectral power of basic EEG frequency ranges independently for first, second and third minutes of the resting state in patients with Parkinson’s disease and healthy patients in the early and late adult age. In experimental groups the result of natural aging was the reduction of power EEG-ranges 4-6 Hz, 6-8 Hz, 9,5-11 Hz and 11-13 Hz. There weren’t significant differences in theta2 band (6-8 Hz) in patients with Parkinson’s disease, in the control group significant differences in this EEG band were typical on the second and third minute of the resting state. It was shown, in group of patients with Parkinson’s disease only in third minute of the resting state the power of theta2 band (6-8 Hz) were significantly higher than in healthy patients. These differences were registered in most cases in the left cerebral hemisphere. This experimental data points to more quickly intensification of the rest state and the reduction of neocortex activity in patients with Parkinson’s disease

Keywords


Parkinson's disease; resting state EEG; theta band; spectral power; aging

References


Аракелян Р.К. Особенности пространственной организации ЭЭГ при использовании амантадин-сульфата у больных болезнью Паркинсона и в эксперименте (Features of the spatial organization of EEG using amantadine sulphate in patients with Parkinson's disease and in the experiment) / Автореферат дис. канд. мед. наук. – M. – 2004. – 28 с.

Габова А.В. Использование вейвлет-преобразований для анализа электрической активности мозга при болезни Паркинсона (Using wavelet transforms for analysis of the brain electrical activity in Parkinson's disease) / А. В. Габова, В.В.Гнездицкий, А.В. Карабанов и др. // Атмосфера. Нервные болезни. – 2012 . – N 3 . – С. 2-7 .

Крыжановский Г. Н. Болезнь Паркинсона (Parkinson's disease) / Крижановский Г. Н., Карабань И. Н., Магаева С. В. и др. // М.: Медицина. – 2002. – 336 с.

Завалишин И.А. Нейродегенеративные болезни и старение (Neurodegenerative diseases and aging) / Завалишин И.А., Яхно Н.Н., Гаврилова С.И. // М: МЕДпресс. – 2001. – 454 с.

Фокина Ю.О. Вероятные механизмы генерации электроэнцефалограммы (Possible mechanisms for the elektroentsefalogram generation) / Фокина Ю.О., Павленко В. Б., Куличенко А. М. // Учебные записки. – 2007. – № 4. – С.96– 108.

Morita A. Relationship between slowing of the EEG and cognitive impairment in Parkinson disease / Morita A., Kamei S., Mizutani T. // J. Clin. Neurophysiol. – 2011. – Vol. 28, № 4. – P.384-387.

Serizawa K. Comparison of quantitative EEGs between Parkinson disease and age-adjusted normal controls / Serizawa K., Kamei S., Morita A. et al. // J. Clin. Neurophysiol. – 2008. – Vol. 25, № 6. – P.361-366

Babiloni C. Cortical sources of resting state electroencephalographic rhythms in Parkinson's disease related dementia and Alzheimer's disease / Babiloni C., De Pandis M., Vecchio F. et al. // Clin. Neurophysiol. – 2011. – Vol. 122, № 12. – P.2355-2364.

Michalowska M. Analysis of causes for falls in people with Parkinson's disease / Michalowska M., Krygowska-Wajs A., Jedynecka U. et al. // Neurol. Neurochir. Pol. – 2002. - № 36. – P.57-68.

Olde Dubbelink K. T. Cognitive decline in Parkinson's disease is associated with slowing of resting-state brain activity: a longitudinal study / Olde Dubbelink K. T., Stoffers D., Deijen J. B. et. al. // Neurobiol Aging. – 2013. – Vol. 34(2). – P. 408-418.


Full Text: PDF (Українська)

Refbacks

  • There are currently no refbacks.
Archive
2014 2 36
2015 2 19
2016 1 2
2017 1 2
2018 1 2
2019 1 2

Requirements for registration of articles

User

Information

Journal Content

Browse

Language