The Role of Histamine in the Regulation of Bile Secretory Function, Circulation and Tissue Respiration of Liver

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Published: Jan 23, 2016
Keywords:
liver, histamine, bile acids, hepatic portal vein, blood supply, oxygen consumption

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Atamnakh Salakh
Київський національний університет імені Тараса Шевченка
P. I. Yanchuk
Київський національний університет імені Тараса Шевченка
E. N. Reshetnik
Київський національний університет імені Тараса Шевченка
S. P. Veselskii
Київський національний університет імені Тараса Шевченка
V. I. Komarenko
Київський національний університет імені Тараса Шевченка
Y. A. Levadianskaia
Київський національний університет імені Тараса Шевченка
E. V. Bondzyk
Київський національний університет імені Тараса Шевченка
A. A. Terekhov
Київський національний університет імені Тараса Шевченка

Abstract

In acute experiments on rats, the intraportal introduction of histamine (8 mg / kg) causes a narrowing of the blood vessels of the liver, so that oxygen supply to its functional elements is reduced. At the same time, autokoid inhibits the oxygen consumption by the liver and energy dependent synthesis of free primary bile acids and their hydroxylation; but it enhances the conjugation with taurine and glycine. These effects of histamine are realized through the Н1-receptor

Article Details

Issue
Vol. 335 No. 2 (2015): Visnyk Cherkas'koho universytetu: seriya biolohichni nauky [Cherkasy University Bulletin: Biological Sciences series]
Section
Статті

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